Description

Retinoic acid early transcript 1E (RAET1E). Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.


Clinical trials

NCT04107142 - Colorectal Cancer, Prostate Cancer, Sarcoma


Target gene expression

The following plot describes the expression, in different tissues and TCGA cancers, of the different isoforms of the gene RAET1E.


Target essentiality


Protein properties

The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present.